Polynucleotide treatment is rapidly emerging as one of the most exciting advancements in aesthetic medicine, offering a natural and regenerative approach to skin rejuvenation. Unlike traditional cosmetic procedures that aim to mask or fill imperfections, polynucleotides work at the cellular level to repair, hydrate, and restore skin health from within. This innovative treatment is gaining popularity among individuals seeking subtle, long-term improvements in skin texture, tone, and resilience without drastically altering their appearance.
Polynucleotides are purified DNA fragments, typically derived from fish sources like salmon, known for their compatibility with human tissue. When injected into the skin, they trigger a regenerative process that stimulates fibroblasts, the cells responsible for producing collagen and elastin. This stimulation enhances skin elasticity, reduces fine lines, improves hydration, and supports tissue healing. The treatment is especially suitable for those with dry, damaged, or ageing skin, and can also help reduce scarring and signs of fatigue around the eyes and mouth.
One of the reasons polynucleotides treatment are gaining traction is their ability to deliver gradual, natural-looking results. Rather than offering instant plumping like dermal fillers, polynucleotides improve the skin’s overall health and structure over several weeks. This makes the treatment particularly appealing to those who prefer subtle enhancements and want to avoid the overfilled look sometimes associated with cosmetic injections. Over the course of multiple sessions, patients often notice firmer skin, reduced wrinkles, and a brighter complexion that continues to improve over time.
The procedure itself is relatively quick and minimally invasive. After an initial consultation, the practitioner cleanses the treatment area and administers a series of small injections using a fine needle. Most people tolerate the procedure well, experiencing only minor discomfort. Temporary redness, swelling, or mild bruising may occur but usually resolves within a couple of days. There is little to no downtime, allowing patients to resume normal activities shortly after treatment.
Polynucleotide therapy is also being embraced by professionals for its versatility. It can be used on various parts of the body, including the face, neck, décolletage, and even the scalp to support hair restoration. It is often combined with other aesthetic procedures such as microneedling or laser treatments to enhance outcomes. The treatment is suitable for all skin types and tones and is considered safe due to its biocompatible and non-immunogenic nature.
As the demand for regenerative and preventative skincare continues to grow, polynucleotides represent a shift toward treatments that prioritize long-term skin health. Their foundation in medical science, originally developed for wound healing and tissue repair, lends credibility to their use in aesthetics. The ability to improve the skin’s natural ability to heal and renew sets this treatment apart in an industry that increasingly values subtlety, safety, and sustainability. Whether used as a standalone therapy or as part of a broader skin maintenance plan, polynucleotide treatments offer a compelling option for those looking to enhance their appearance through natural regeneration.